Tuesday, September 6, 2011

triptorelin acetate

1 Triptorelin acetate
2 PREPARATION AND TRIPTORELIN INJECTION
3 GMP
4.Stimulating breeding
Trptorelin Acetate
5-oxo-pro-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NH
2
CH
3
COOH
C
64
H
82
N
18
O
13
,xC
2
H
4
O
2


Acton
and use
Gonadotrophin-releasing
Preparation
Trptorelin Injection
DEFINITION
Trptorelin acetate is the acetate form of a hypothalamic peptide that stimulates the release of follicle-stimulating and luteinising from the pituitary gland.It contains not less than 95.0per cent and not more than the equivalent of 102.0 per cent of the peptide C
56
H
78
N
16
O
12
,calculated with reference to the anhydrous,acetic acid-free substance.It is obtained by chemical synthesis.

CHARACTERS
A white or slightly yellowish powder,soluble in water and in a 1 percentV/Vsolution of glacial acetic acid,sparingly soluble in methanol.

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