Tuesday, September 6, 2011

tretinoin/vitamin a acid

tretinoin/vitamin a acid
97.0--103.0% yellow or orange crystallline powder
ISO, GMP, HACCP, SGS certified
OEM&ODM maufactue

Product
:
tretinoin/vitamin a acid

CAS NO.:
302-79-4

EINECS NO:
206-129-0

M.F.:
C
20
H
28
O
2

M.W.:
300.44

Metaling point :
179-184 ºC

Spec:
USP28
package : 25KG/DRUM,5KG







CAS#: 302-79-4
Molecular Formula: C20H28O2
Molecular Weight: 300.44
Quality Standard: USP26
Name: Tretinoin or Vitamin A Acid
CAS#: 302-79-4
Molecular Formula C
20
H
28
O
2
Molecular Weight 300.44
Synonyms 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; all-trans-Retinoic acid; Vitamin A acid.
Character: Yellow acicular crystals, trans tretionoirum mainly. Easily dissolved in chloroform, dichoromethane and dissolved in carbinol, ethanol and also dissolved in vegetable oil and lipid. Instability exposed in light and caloricr, easily absorbing moisture and metamorphosed in water.
Quality index: Conform CP2005/BP2002/USP26
Melting point: About 182 centigrade
Loss on drying: d0.5%
Heavy metals: d0.002% Content: e98~102%
Function: Both tretionirum and Vitamin A can stimulate skin growth and keep epidermic normal. Howerver, to spread on part of skin has no actual effect. Taking orally vitamin A is benefit to treat skin disorders. Applying vitamin A acid to skin partly could produce intensive pharmacological action. External use can slow down skin aging process for solarization, remove tiny wrinkles, and reduce skin roughness, so skin will become ruddy.
Function and Usage: Tretinoin is the acid form of vitamin A and so also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris.. It is also used to treat acute promyelocytic leukemia (APML).
Test/Observation
Specifications
Result
Assay Content HPLC
97%-102%
99.12%
Appearance
Fine Powder
Complies
Identification
IR.UV
Complies
Odor
Characteristic
Complies
Mesh
100% pass 100 mesh
Complies
Residue on ignition
MAX 0.1%
Complies
Loss on drying %
MAX 0.5%
0.39%
Ash %
MAX.1.0%
0.52%
Heavy metals PPM
MAX.0.002%
Complies
Limit of Isotretinoin
MAX5.0%
3.9%
Organic Volatile Impurities
Meet The Requirements
Complies
Microbiology
Total Plate Count
Yeast & Mold
E.Coli
Salmonella

<1000cfu/g
<100cfu/g
Negative
Negative

82cfu/g
Negative
Complies
Complies
Conclusion

We are profession herbal extract manufacture in china.,We can supply many kinds of
herbal extract powder from our GMP factory, Usually with 1 Ton in stock. 100% Natural, No pollution and have a nice color.
Please do not hesitate to contact me for any questions!
Waiting for your good news!

Thanks for your patience!

Best wishes

Dorothy




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