Simvastatin

Simvastatin
CAS No. 79902-63-9
treat hypercholesteremia patients
1. it is used to treat hypercholesteremia patients
2. Inhibits hypertension-induced cardiac hypertrophy in rats

Test
Standard
Result
Identification:
Positive
Positive
Specific rotation :
+ 285º ----+ 298º
+ 292º
Solubility :
soluble in chloroform, Methanol and ethanol
conforms
Loss On drying :
≤0.5 %
0.24%
Residue on Ignition
≤0.1%
0.03%
Heavy Metals:
≤20ppm
<20ppm
Limit Of Lovastatin :
≤1.0%
0.1%
Chromatographic Purity:
Major≤0.4%
conform
Total≤1.0%
conform
Assay (On Dry Basis):
98.0-101%
99.44%