Sunday, September 4, 2011

64228-81-5

Atracurium besylate
1.CAS NO.64228-81-5
2.Purity:99% min
3.Neuromuscular Blocking Agent
4.Apper: white to pale yellow powder
5.Specifications
CHARACTERISTICS
A WHITE TO PALE YELLOW POWDER OR FLAKY CRYSTALS HYGROSCOPIC
SOLUBILITY
VERY SOLUBLE IN ACETONITRILE AND CHLOROFORM SOLUBLE IN WATER AND PRACTICALLY INSOLUBLE IN ETHER
IDENTIFICATION
UV
LR
PH
3.5-5.0
APPEARANCE OF SOLUTION
CLEAR TO YELLOW STANDARD NO.7
METHYL BENZENESULPHONATE
≤10PPM
TOLUENE
≤890PPM(ICH)
RELATED SUBSTANCES
TOTAL IMPURITIES
≤7.0%
IMPURITY F
≤3.0%
ANY OTHER SECONDARY IMPURITY
≤2.0%
ISOMER RATIO
CIS-CIS
56.0%~60.0%
CIS-TRANS
34.5%~37.5%
TRANS-TRANS
5.0%~6.5%
LOSS ON DRYING
≤3.0%
SULPHATED ASH
≤0.2%
ASSAY
97.0%~103.0%

6.
Uses and Indications

Atracurium is indicated as an adjunct to general anesthesia to produce muscle relaxation during surgical procedures or mechanical ventilation and also to facilitate endotracheal intubation. Atracurium can be used in patients with significant renal or hepatic disease.


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. Advantages:
(1) 25 year experience in pharmaceutical and botanical industry
(2) ISO9001:2008 certificated company
(3) stable business relations with most of the GMP sources in China

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