High purity Vinblastine Sulfate

* USP33
* GMP-certified producer;
* NDC No., US-DMF No. & open part available
* Exported to North american market regularly

Name:Vinblastine sulfate
Synonyms:Vincaleukoblastine sulfate salt
Molecular Formula:C46H58N4O9.H2SO4
Molecular Weight:909.06
CAS:143-67-9
EINECS:205-606-0
Appearance: White or kind of white loose form or amorphous solid
Indication: Mainly used for the treatment of solid tumor. For malignant lymphoma, testicular neoplasm and choriocarcinoma curative effect is better. For lung, breast, ovarian, skin cancer, renal mother cell tumor and monocytes leukaemia also have certain curative effect.
Pharmacology: Vinblastine Vinca plants for the oleander extract has anti-cancer activity of an alkaloid. Major inhibition of tubulin polymerization, preventing the formation of spindle microtubules, so stop in mid-mitosis. Role in the cell membrane can also interfere with membrane transport of amino acids, protein synthesis was inhibited, also inhibited RNA synthesis.
Main Specs:
Appearence: A white or almost white, crystalline powder
Solubility: Freely soluble in Water
pH value: 3.5 to 5.0
Loss on drying: 15.0% max
Any individual impurity: 1.0% max
Total impurities: 3.0% max
Residual solvents:
Ethanol: 5000ppm max
Methanol: 3000ppm max
Chloroform: 60ppm max
Dichloromethane 600ppm max
Microbial Limit:
Bacteria: 1000cfu/g max
Fungi: 100cfu/g max
Escherichia coli: Not found
Assay: 96.0% to 102.0%