Cisatracurium Besylate

Cisatracurium Besylate
* Assay: above 95%
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Cisatracurium Besylate
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CAS No: 96946-42-8
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Property:
M.Wt:
C65H82N2O18S2=1243.50
Appearance:
a white to pale yellow powder
LogS:
-7.47
LogP:
3.34
PKa:
19.62
Refractivity:
280.68
Polarizability:
105.55
Water solubility:
4.17g/ml
Hydrogen acceptor count:
10
Hydrogen donor count:
0
Polar surface area:
126.44
Rotatable bond count:
28
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Package and storage:
Store vials in refrigerator(36°F to 46°F) in original carton. Do not freeze . May be removed from refrigerator and stored at controlled room temperature(59°F to 86°F) but injection must be used within 21days even if refrigerated.
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-Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium Besylate acts on cholinergic receptors, blocking neuromuscular transmission.
-This action is antagonized by acetylcholinesterase inhibitors such as neostigmine.
-The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started.
-As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action.