Benzylpenicilin Benzatine + 1% Lecithin Sterile 150 microns

Penicillin (sometimes abbreviated PCN or pen) is a group of antibiotics derived from Penicillium fungi.ISO22000, HACCP, GMP
Mechanism of action
Main article:
β-lactam antibiotics work by inhibiting the formation of in the bacterial . The moiety () of penicillin binds to the () that links the peptidoglycan molecules in bacteria, which weakens the cell wall of the bacterium (in other words, the antibiotic causes or death due to pressure). In addition, the build-up of peptidoglycan precursors triggers the activation of bacterial cell wall hydrolases and autolysins, which further digest the bacteria's existing peptidoglycan.
bacteria are called when they lose their cell wall. bacteria do not lose their cell wall completely and are called after treatment with penicillin.
Developments from penicillin
The narrow range of treatable diseases or
spectrum of activity
of the penicillins, along with the poor activity of the orally active phenoxymethylpenicillin, led to the search for derivatives of penicillin that could treat a wider range of infections. The isolation of , the nucleus of penicillin, allowed for the preparation of semisynthetic penicillins, with various improvements over (bioavailability, spectrum, stability, tolerance).
The first major development was , which offered a broader spectrum of activity than either of the original penicillins. Further development yielded -resistant penicillins including , and methicillin. These were significant for their activity against beta-lactamase-producing bacteria species, but are ineffective against the strains that subsequently emerged.
Another development of the line of true penicillins was the antipseudomonal penicillins, such as , , and , useful for their activity against Gram-negative bacteria. However, the usefulness of the beta-lactam ring was such that related antibiotics, including the , the and, most important, the , still retain it at the center of their structures.